Tyler Wittmer's sermon "Be Patient with Them All" centers on Paul's exhortation in 1 Thessalonians 5:14, urging respect for church leaders, fostering unity, and providing support and guidance to believers. He stresses patience, likening it to Christ's enduring grace and love, and calls for repentance for non-believers. The sermon emphasizes the church's role in admonishing the idle, comforting the faint-hearted, and aiding the weak, highlighting the community's responsibility to support one another in spiritual growth and faith.